Природный порошок диосгенина 95% HPLC

Что такое диосгенин?

Диосгенин, широко известный как диосгенин, представляет собой своего рода стероидный диосгенин, который естественным образом синтезируется растениями и широко распространен в клубнях зернобобовых и диоскореечных растений. Является важным сырьем для синтеза стероидных гормональных препаратов. Он имеет много замечательных фармакологических эффектов, таких как противоопухолевые, противовоспалительные, антиоксиданты, и имеет высокую лекарственную ценность.

Зеленый источник обеспечивает диосгениновый порошок, извлеченный из диких ямовых клубней. Это природный дхеа (дегидроэпиандростерон), который может способствовать метаболизму эпидермальных клеток кожи, повысить увлажняющую функцию кожи, а также помочь улучшить физическое состояние.

Green Spring Technology was established in 2000 and is a professional supplier of natural ingredients and a solution provider. All products adhere to the highest international industry standards, complying with EU EC 396, EU 2023/915 standards, and the highest solvent residue standards. We have a comprehensive quality management system in place, strictly organising production following ISO, HACCP, and other quality standards. We have obtained certifications including Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO 9001, ISO 22000, EU Organic, and USDA Organic. Green Spring boasts an outstanding R&D team, an experienced production team, and a professional sales team. We can customise various standard extracts and proportionate extracts. We also provide authoritative third-party testing reports.

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Benefits:

Antitumor Activity

In vivo and in vitro studies have shown that diosgenin has cytotoxicity to a variety of tumor cells, including breast cancer cells, colon cancer cells, prostate cancer cells, lung cancer cells, gastric cancer cells, Osteosarcoma cells, etc. It can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking cell cycle, and anti-tumor metastasis.

Hepatoprotective Effect

Diosgenin powder can effectively inhibit the cell viability of HSC-T6, LX-2, and primary rat hepatic stellate cells (HSCs), while liver cells are not affected. Diosgenin also has a good protective effect on alcoholic liver injury, which is achieved by reducing oxidative stress, the production of inflammatory cytokines, cell apoptosis, and liver steatosis.

Hypoglycemic Effect

The combination of NPH insulin and diosgenin in the treatment of elderly type 2 diabetes is more effective in reducing blood sugar with good safety, which may be related to the reduction of Glycated hemoglobin formation.

Anti Osteoporosis Effect

Dioscin can promote the proliferation of osteoblasts and inhibit the formation of Osteoclast. Research has shown that after diosgenin treatment of MC3T3-E1 cells, ER- α、 ER- β、 Lrp5 β- The expression of both catenin and Bcl-2 proteins increased, and the ratio of OPG/RANKL increased, depending on the LRP5 pathway, thereby promoting osteoblast proliferation.

Applications:

Pharmaceutical Intermediate:

Diosgenin powder is an important steroidal saponin and an important raw material for Semisynthesis steroidal compounds.